Marthasville is an incorporated city in Warren County, Missouri, United States. The Katy Trail, a 225-mile long bike path, passes through Marthasville, and the original grave of Daniel Boone is located here. In 1845, Boone’s remains were believed to be disinterred and moved to Kentucky for reburial but, over the years, a legend arose that Boone’s remains never left Missouri and that he still rests on a small knoll just outside the city limits. Because of the many wineries from here east to Defiance, Marthasville is considered to mark one end of the “Missouri Weinstrasse”.

As of the census of 2010, there were 1,136 people, 431 households, and 310 families residing in the city. The population density was 1,336.5 inhabitants per square mile (516.0 /km2). There were 478 housing units at an average density of 562.4 per square mile (217.1 /km2). The racial makeup of the city was 97.5% White, 0.2% African American, 0.3% Native American, 0.1% Asian, 0.7% from other races, and 1.2% from two or more races. Hispanic or Latino of any race were 1.8% of the population.

Marthasville was named one of 2015’s Top Ten Safest and Most Peaceful Smaller Places to Live in Missouri by the online site, Only In Your State. Marthasville’s crime rate is much lower than both the Missouri and national average. There were only six reported crimes in 2013 and none of them were violent crimes.

Marthasville is located 3 miles from the Washington Regional Airport, 22 miles from the Spirit of St. Louis Airport and 48 miles from Lambert St. Louis International Airport.